与炎症性肠道疾病相关的常规和非常规性失育症 - 一个单一中心的经验
Anita Sejben1, Zsófia Balajthy1, Zsófia Krisztina Török1
1Department of Pathology, University of Szeged, 6725 Szeged, Hungary.
Medical sciences (Basel, Switzerland)
|February 20, 2026
概括
非传统的发育不良发生在28%的炎症性肠病 (IBD) 患者中,这些患者患有瘤病变. 加强组织病理学评估和加强监测对于管理IBD相关的发育不良至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
- 在瘤学瘤学.
背景情况:
- 炎症性肠病 (IBD) 与结直肠癌的风险增加有关.
- 最近的研究已经在IBD患者中发现了各种非传统的可塑性损伤.
- 描述这些病变对于风险分层和风险管理至关重要.
研究的目的:
- 在IBD患者中描述和比较常规和非常规的功能障碍.
- 为了确定在匈牙利南部的人口中这些缺血症的患病率.
- 为了确定与IBD相关性发育不良等相关的因素.
主要方法:
- 连续一组IBD患者 (2011-2023) 的回顾性分析.
- 根据当前的病理学标准重新分类超塑性或瘤样本.
- 统计分析,以确定患者特征和失育症亚型之间的关联.
主要成果:
- 在有可评估样本的176名IBD患者中,74%患有常规发育不良,28%患有非常规发育不良.
- 年龄较大和男性性别与常规发育不良的几率较高有关.
- 结直肠癌的发展和先进的M阶段与常规发育不良的几率较低有关.
结论:
- 在IBD患者的瘤病变中,非传统的形症占有很大比例 (28%).
- 彻底的组织病理学评估对于确认完全切除异形性病变至关重要.
- 强化监测策略可能有利于IBD患者的成形障碍,特别是非传统类型.
相关概念视频
Inflammatory Bowel Disease II: Crohn's Disease
1.3K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.3K
Inflammatory Bowel Disease V: Surgical Management
747
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
747
Chronic Bowel Disorders: Introduction
829
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
829
Inflammatory Bowel Disease I: Ulcerative Colitis
1.2K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.2K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
950
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
950
Inflammatory Bowel Disease IV: Pharmacological Management
832
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
832


