其他健康儿童的严重下尿路功能障碍:三个案例系列和叙述审查
Olivia-Oana Stanciu1,2, Andreea Moga1,2, Laura Balanescu1,2
1Department of Pediatric Surgery and Orthopedics, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Pediatric reports
|February 20, 2026
概括
在儿童中,严重的功能性下尿道功能障碍 (LUTD) 是罕见的,但可以模仿结构问题. 早期泌尿动力学诊断和保守的管理是预防并发症和保护功能的关键.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 功能性泌尿器科 功能性泌尿器科
- 儿科脏病学 儿科脏病学
背景情况:
- 在神经和解剖学上正常的儿童中,严重的下泌尿道功能障碍 (LUTD) 不常见,并且往往被诊断不足.
- 功能性排泄障碍可以模仿阻塞性或反流性病理,导致误诊和潜在的上部泌尿道损伤.
研究的目的:
- 突出儿童严重功能性LUTD的异质性和潜在可逆性.
- 强调早期泌尿动力学评估对于准确的诊断和管理的重要性.
主要方法:
- 介绍了三起儿科病例 (3-10岁) 患有严重的功能性LUTD.
- 泌尿动力学评估以确定不同的功能表型.
- 多模式的保守管理包括泌尿疗法,生物反,药物治疗和导管治疗.
主要成果:
- 泌尿动力学表型学揭示了各种功能性问题:detrusor过度活跃,detrusor-sphincter与反流 (Hinman综合征) 的不协同作用,以及detrusor活动不足.
- 所有患者在囊泡镜检查中都显示出膀壁的重塑.
- 在大多数情况下,保守的治疗导致了感染的解决和膀功能的改善.
结论:
- 在儿童中,严重的功能性LUTD是异质的,但可能是可逆的.
- 早期泌尿动力学评估对于区分功能性和结构性疾病以及指导治疗至关重要.
- 以功能为导向的保守管理是保护功能有效治疗的基石.
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