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生殖寿命与绝经后代谢综合征之间的关联:在中国进行的一项横截面研究

Xin Huang¹, Yuanyuan Hua²

¹Chongqing Medical University, Chongqing, China.

Menopause (New York, N.Y.)

|February 20, 2026

概括

绝经后妇女的生殖时间较长与代谢综合征 (MS) 的更高患病率有关. 这一发现突显了生殖史作为理解这一群体中多发性硬化风险的关键因素.

科学领域:

生殖内分泌学生殖内分泌学
代谢健康代谢健康
公共卫生公共卫生

背景情况:

代谢综合征 (MS) 患病率在绝经后妇女中正在上升.
在这个人口群体中,多发性硬化症的病因仍然不完全理解.
关于生殖寿命和MS的研究产生了不一致的结果.

研究的目的:

调查绝经后妇女生殖周期和代谢综合征 (MS) 之间的关联.
为了澄清生殖史对MS风险的影响.
为了解绝经后妇女的MS病因提供见解.

主要方法:

采用2015年中国健康与退休纵向研究 (CHARLS) 数据进行的横截面研究.
包括2,801名参与者的问卷数据,体检和血液测试.
用多变量逻辑回归分析来评估这种关系.

主要成果:

延长生殖寿命与肥胖,高血压和高血糖症的患病率增加相关 (P<0.05).
在对共变量进行调整后,更长的生殖寿命是MS的重要预测因素 (OR=1.019,P=0.042).
生殖寿命为32-35岁和≥36岁的妇女患MS的几率显著更高 (OR分别为1.305和1.381).

结论:

更长的生殖时间与更高的代谢综合征在绝经后妇女的患病率有关.
生殖周期在这个人群中成为MS的重要风险因素.
这些发现强调了在MS预防策略中考虑生殖史的重要性.

关键词:

第一次月经的年龄.绝经的年龄绝经的年龄查尔斯数据库查尔斯数据库代谢综合征是代谢综合征.绝经后的时期是绝经后的时期.生殖寿命可以延长.

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