脊髓刺激在治疗耐火性上肢疼痛方面的临床有效性
Yanisa Ingkapassakorn1, Songrit Vuttipongkul1, Bunpot Sitthinamsuwan2,3
1Division of Neurosurgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lang Road, Bangkok Noi, Bangkok, 10700, Thailand.
Neurosurgical review
|February 20, 2026
概括
脊髓刺激 (SCS) 有效地治疗严重的上肢疼痛. 这种疗法显著降低了大多数患者的疼痛评分,无论疼痛是什么.
科学领域:
- 神经学 神经学
- 疼痛管理 疼痛管理
- 神经外科 神经外科
背景情况:
- 与下肢疼痛相比,脊髓刺激 (SCS) 在上肢疼痛方面未得到充分利用.
- 有限证据表明SCS在耐火性上肢疼痛中的有效性.
研究的目的:
- 为了评估SCS对严重,耐火的上肢疼痛的有效性.
- 为了比较不同疼痛病因的SCS结果,包括神经与非神经病变和复杂区域疼痛综合征 (CRPS).
主要方法:
- 对13名经过SCS试验的耐火性上肢疼痛患者的前性评估.
- 11名患者在成功试验后进行了永久的SCS植入.
- 数字疼痛评分表 (NPRS) 评分,采集在手术前和手术后.
- 根据病变类型 (神经/非神经) 和诊断 (CRPS/非CRPS) 的亚组分析.
主要成果:
- 植入后的NPRS平均得分显著下降,从9.5降至3.6 (p < 0.001).
- 在所有评估小组中观察到显著的疼痛减轻 (p < 0.05).
- 在神经/非神经病变或CRPS/非CRPS组之间没有发现疼痛减轻幅度的显著差异.
结论:
- SCS是一种有效的治疗各种原因的耐火性上肢疼痛.
- SCS的疗效并不取决于特定的疼痛病因,包括CRPS.
- SCS显示,对于患有严重上肢疼痛的患者来说,具有广泛的潜在益处.
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