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相关概念视频

Embryonic Stem Cells00:57

Embryonic Stem Cells

5.5K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
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Embryonic Stem Cells00:58

Embryonic Stem Cells

33.0K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
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Stem Cell Culture01:17

Stem Cell Culture

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
6.2K
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

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Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
5.7K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

28.2K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
28.2K
Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

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Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
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相关实验视频

Updated: Feb 22, 2026

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
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Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats

Published on: March 30, 2018

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干细胞与野生动物保护

Gabriela Mastromonaco1, Paula Mackie2, Virginia Russell2

  • 1Reproductive Sciences Unit, Toronto Zoo, Toronto, ON, Canada. gmastromonaco@torontozoo.ca.

Advances in experimental medicine and biology
|February 20, 2026
PubMed
概括

干细胞技术为物种保护提供了新的希望,基于辅助生殖技术 (ARTs). 当前的挑战包括低效率和遗传不稳定性,阻碍了这些先进的干细胞方法的应用.

关键词:
危物种 危物种 危物种在体外系统的体外系统.重编程 重编程 是一种重编程.身体细胞是体细胞.干细胞是一种干细胞.野生动物生殖繁殖 野生动物生殖繁殖

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科学领域:

  • 生殖生物学和保护科学.

背景情况:

  • 50多年来,辅助生殖技术 (ART) 已被用于物种保护.
  • 对于危物种而言,ART依赖于获得繁殖活跃动物,这是一个重大障碍.
  • 最近的干细胞进步,包括诱导多能干细胞和ex vivo发生,显示出希望.

研究的目的:

  • 审查与生殖医学相关的关键干细胞技术.
  • 专注于将这些干细胞技术应用于物种保护工作.

主要方法:

  • 审查关于干细胞技术及其在生殖医学中的应用的科学文献.
  • 分析诱导多能干细胞和ex vivo生成系统的进展.
  • 探索将这些技术应用于野生动物保护的潜力和挑战.

主要成果:

  • 干细胞技术提供了一种新的方法来补充现有的ART用于保护.
  • 干细胞研究的进展为野生动物应用和生物银行提供了基础.
  • 仍然存在重大挑战,包括干细胞的低效率和遗传不稳定性.

结论:

  • 干细胞技术在促进物种保护方面具有相当大的潜力.
  • 克服当前的技术限制对于成功实施保护育种计划至关重要.
  • 需要进一步的研究来将干细胞的潜力转化为实际的保护解决方案.