相关实验视频
Updated: Feb 22, 2026
05:34
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
Published on: April 4, 2025
1.8K
2021年病的现实世界采用:改善全球结果 慢性病中的血压指南
Hyeok-Hee Lee1, So Mi Jemma Cho2,3,4, Cian P McCarthy5,6
1Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Journal of the American Society of Nephrology : JASN
|February 20, 2026
概括
2021年病:改善全球结果 (KDIGO) 慢性病 (CKD) 血压 (BP) 准则显示现实世界的采用有限. 截至2024年,大多数CKD患者仍然高于推的缩血压目标.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 心脏病学 心脏病学
- 临床实践指南 临床实践指南
- 公共卫生 公共卫生
背景情况:
- 2021年病:改善全球结果 (KDIGO) 准则建议慢性病 (CKD) 患者降低缩血压 (BP) 目标 (<120 mmHg).
- 这个更新的指南对临床实践的实际实施和影响在很大程度上仍未得到审查.
研究的目的:
- 评估2021年KDIGO静脉血压目标在CKD3-4期患者的采用率.
- 评估遵守2021年KDIGO系统性BP目标和临床结果之间的关联.
主要方法:
- 从2020年到2024年,每年在Mass General Brigham医疗保健网络中对大约5万名CKD阶段3-4的患者进行连续的横截面分析.
- 对18996名发生性CKD第3-4期 (2014-2019) 的患者进行了纵向分析,以评估基于缩血压相对于2021年KDIGO目标的临床结果.
主要成果:
- 在指导方针之前 (2020年),18.3%的CKD患者达到静脉血压目标. 在指南发布后,采用率略有增加,到2024年达到21.9%.
- 患有缩血压高于2021年KDIGO目标的患者表现出心脏脏事件的风险增加,但低血压风险较低.
- 在患者之间没有观察到其他安全性终点的显著差异,高于或低于目标缩血压.
结论:
- 对于CKD患者来说,2021年KDIGO血压指南的现实世界采用是有限的.
- 在2024年,绝大多数 (近80%) 的CKD患者仍然高于推的缩血压目标.
相关概念视频
01:28Chronic Kidney Disease III: Interprofessional Care
503
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
503
01:25Chronic Kidney Disease I: Introduction
820
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
820
01:18Chronic Kidney Disease IV: Nursing Management
441
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
441
01:24Chronic Kidney Disease II: Clinical Manifestations
758
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
758
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
363
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
363
01:28Kidney Transplant I: Introduction
552
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
552