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Updated: Feb 22, 2026

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单细胞表观遗传分析显示,ccRCC中的瘤内在干扰素反应程序与预后不佳和BAP1损失有关

Sabrina Y Camp1,2, Meng Xiao He1,2,3, Michael S Cuoco2,4

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

Science advances
|February 20, 2026
PubMed
概括

BAP1-突变细胞癌 (RCC) 呈现出与预后不佳相关的干扰素反应. 这表明,准干扰素信号传递和免疫逃避途径可能是对攻击性RCC的治疗策略.

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