在狗的计算机断层扫描检查后,静脉注射的有的对比剂可以暂时增加尿液的比重和pH,而不会影响其他尿液分析参数
Swann Barthe1, Cécile Dor2, Delphine Rault1
11Diagnostic Imaging Department, AzurVet, Saint-Laurent-Du-Var, France.
Journal of the American Veterinary Medical Association
|February 20, 2026
概括
对比剂Iopromide在CT扫描后的狗中暂时影响尿液的特异重量和pH. 其他尿分析参数,如蛋白尿,保持不变,允许可靠的临床决定.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 诊断成像 诊断成像 诊断成像
- 临床病理学 临床病理学
背景情况:
- 增强对比度的计算机断层扫描 (CT) 是兽医学中常见的诊断工具.
- 伊奥普罗米德是一种非离子离子对比剂,经常用于CT扫描期间静脉注射.
- 了解对比剂对诊断测试的直接影响对于准确的患者评估至关重要.
研究的目的:
- 评估iopromide对狗的关键尿液分析参数的直接影响.
- 为了评估尿液特异性重量 (USG) 的变化,尿液测量棒的发现,尿液沉积物和尿液蛋白与肌素比率 (UPCR) 在对比剂施用后.
主要方法:
- 一项前性研究,涉及30只客户拥有的狗,用iopromide进行CT扫描.
- 在静脉注射对比剂 (IVIC) 施用前立即和施用后30分钟内,采集了尿液样本.
- 对所有采集的样本进行了标准实验室分析.
主要成果:
- 在IVIC后,尿液中位特重量 (USG) 从1.046到1.058显著增加.
- 在IVIC给药后,尿液中位pH值从6.25显著增加到7.
- 在其他尿液测量棒参数,尿液沉积物或UPCR中没有发现显著变化.
结论:
- 静脉注射iopromide会导致狗体内USG和尿液pH的暂时变化.
- 大多数其他的尿分析参数,包括蛋白尿和沉积物分析,都没有受到胺胺的显著影响.
- 这些发现支持大多数尿液分析参数的可靠性,用于在接受对比剂的狗中立即进行临床决策.
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