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Updated: Feb 22, 2026

Quantitative Localization of a Golgi Protein by Imaging Its Center of Fluorescence Mass
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Quantitative Localization of a Golgi Protein by Imaging Its Center of Fluorescence Mass

Published on: August 10, 2017

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重新定义了戈尔吉装置的入口和出口

Akihiko Nakano1

  • 1Institute of Integrated Research, Science Tokyo, Tokyo, Japan; RIKEN Center for Advanced Photonics, Saitama, Japan.

Current opinion in cell biology
|February 20, 2026
PubMed
概括

西斯-戈尔吉网络 (CGN) 是动物,植物和酵母细胞之间广泛保存的隔间,在蛋白质运输中发挥着关键作用. 本摘要阐明了它在真核生物中的存在和基本特征.

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Golgi Apparatus01:49

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As they leave the Endoplasmic Reticulum (ER), properly folded and assembled proteins are selectively packaged into vesicles. These vesicles are transported by microtubule-based motor proteins and fuse together to form vesicular tubular clusters, subsequently arriving at the Golgi apparatus, a eukaryotic endomembrane organelle that often has a distinctive ribbon-like appearance.
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Golgi Apparatus

Properly folded and assembled proteins are selectively packaged into vesicles that exit the ER. Motor proteins transport these vesicles to the Golgi apparatus for adding modifications that make these proteins functional at their destination.
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While it is unclear how molecules move between adjacent Golgi cisternae, it is apparent that the molecules move from cis- cisterna, the entry face, to the trans- cisterna, the exit face. Experiments initially suggested vesicles that bud from one cisterna and fuse with the next cisterna to transport proteins between the cisternae. This vesicular transport model describes the Golgi apparatus as a relatively static structure with a unique enzyme composition in each cisterna. Molecules are...
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