没有什么是公平的关于一个浪费的器官;消除出序分配30天减少了难以取代的脏的利用
Christopher Curran1, Jillian Wojtowicz1, James R Rodrigue2
1New England Donor Services.
概括
暂停异序分配 (AOOS) 救援途径对已故捐赠脏的不使用增加了14%,特别是对高KDPI器官. 这凸显了需要制定明确的国家救援拨款战略,以改善脏利用率.
科学领域:
- 移植免疫学 移植免疫学
- 器官采购 器官采购 器官采购
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 顺序外分配 (AOOS) 是一种利用已故捐赠脏的策略,有不使用的风险.
- AOOS对脏整体利用的影响仍然是移植社区内争论的主题.
研究的目的:
- 评估暂时暂停AOOS救援途径对已故捐赠脏利用的影响.
- 在没有AOOS的期间评估脏不使用率的变化.
主要方法:
- 进行了一项前性的,单个器官采购组织 (OPO) 演示项目.
- AOOS的救援途径被暂停了30天,脏被严格按照国家比赛运行顺序分配.
- 干预期间的利用率与12个月的参考期进行了比较.
主要成果:
- 在干预期间,整体脏不使用率从29.1%增加到43.2%.
- 对于较高的脏捐赠者个人资料指数 (KDPI) 脏,观察到更高的非使用率.
- 据估计,如果使用率与参考期保持一致,则会移植13个额外的脏.
结论:
- 暂时暂停AOOS救援途径与脏不使用的显著增加有关,特别是医疗复杂的脏.
- 在没有标准化替代方案的情况下消除救援分配可能会导致器官浪费增加.
- 透明,国家定义的救援分配策略对于优化已故捐赠脏的利用至关重要.
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