水平和粘合性囊炎风险:1:1的倾向匹配分析
Zina Smadi1, Katie McBee2, Bilal Irfan3
1The University of Jordan, School of Medicine, Amman, Jordan.
Journal of shoulder and elbow surgery
|February 20, 2026
概括
较高的正常丸激素水平与结肩膀 (粘合性囊炎) 的风险增加有关. 这项研究表明,激素状况对于评估冷肩风险很重要.
科学领域:
- 内分泌学 在内分泌学.
- 整形外科 整形外科 整形外科
- 流行病学 流行病学
背景情况:
- 粘附性囊炎 (冷的肩膀) 涉及肩膀疼痛和限制运动.
- 内分泌因素,特别是,与它的发展有关.
- 内源性丸激素和粘合性囊炎之间的联系需要进一步调查.
研究的目的:
- 评估血清丸激素水平与发展粘合性囊炎的风险之间的联系.
- 为了在1,2,5年期间评估这种风险.
- 调查替代疗法 (TRT) 在这种关联中的作用.
主要方法:
- 使用TrinetX数据库 (2005-2025) 的回顾性队列研究.
- 包括35岁以上的男性,有记录的丸激素水平,没有先前的肩膀手术.
- 将患者分层分为低 (<300 ng/dL) 和正常高 (300-1000 ng/dL) 的丸激素组.
主要成果:
- 正常高丸激素水平与1年,2年和5年显著增加的粘合性囊炎风险相关 (RR 1.12-1.23).
- 这种关联在排除接受TRT的患者时保持一致.
- 在接受TRT的患者中,风险在5年后升高,但在1年或2年后没有升高.
结论:
- 正常高的内源性丸激素水平与较高的粘合性囊炎风险有关.
- 囊炎风险评估时应考虑荷尔蒙状况.
- 需要进一步的前性研究来证实这些发现.
相关概念视频
Sign Test for Matched Pairs
437
The sign test for matched pairs offers a robust method for comparing two paired samples, often for the effects of an intervention in one of them. This method is very useful in situations where the underlying distribution of the data is unknown. The test compares two related samples—often pre- and post-treatment measurements on the same subjects—to determine if there are significant differences in their median values.
To conduct the sign test, we first calculate the differences in...
To conduct the sign test, we first calculate the differences in...
437
Wilcoxon Signed-Ranks Test for Matched Pairs
513
The Wilcoxon signed-rank test for matched pairs evaluates the null hypothesis by combining the ranks of differences with their signs. It essentially tests whether the median of the differences in a population of matched pairs is zero. Since the test incorporates more information than the sign test, it generally yields more trustable conclusions. This test also does not require the data to follow a normal distribution, but two conditions must be met for it to be applicable: (1) the data must...
513
Relative Risk
2.3K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.3K
Odds Ratio
1.9K
The odds ratio (OR) is a statistical measure used extensively in epidemiology and research to quantify the strength of association between exposure and outcome across different groups. Unlike relative risk, which compares the probabilities of an event occurring, the odds ratio compares the odds of an event occurring in the exposed group to the odds of it occurring in the unexposed group. The odds, in this context, are calculated as the probability of the event happening divided by the...
1.9K


