用Zn(II) 作为辅助剂的基于伊米达的脂质纳米颗粒,用于强大的脏向mRNA传递和增强免疫激活

相关实验视频

Updated: May 8, 2026

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
10:33

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

Published on: July 23, 2016

11.3K

Yu Han1, Guohua Ma1, Kai Zhang2

  • 1State Key Laboratory Base of Eco-Chemical Engineering, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.

Journal of controlled release : official journal of the Controlled Release Society
|February 20, 2026
PubMed
概括

研究人员开发了新的辅助脂质纳米颗粒 (LNP) 以提高mRNA疫苗的输送. 这些基于伊米达的LNP可以改善免疫反应,并显示出对肝外分娩和癌症免疫治疗的前景.

关键词:
免疫接种反应的反应.脂质纳米颗粒的使用方法自动组装自动组装辅助剂是一种辅助剂.提供mRNA的交付.

更多相关视频

Immunostimulatory Agent Evaluation: Lymphoid Tissue Extraction and Injection Route-Dependent Dendritic Cell Activation07:04

Immunostimulatory Agent Evaluation: Lymphoid Tissue Extraction and Injection Route-Dependent Dendritic Cell Activation

Published on: September 16, 2018

10.8K
Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells10:02

Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells

Published on: June 10, 2022

2.7K

相关概念视频

siRNA - Small Interfering RNAs02:30

siRNA - Small Interfering RNAs

Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the ATP-dependent...