阐明右脊侧前额叶皮质在认知运动干扰中的作用:跨直流刺激的极性特异效应
Hiroshi Miura1, Yuji Ogihara1, Yuna Imai2
1Graduate School of Health Sciences, Hokkaido University, Sapporo, 060-0812, Japan; Department of Rehabilitation, Higashinaebo Hospital, Sapporo, 007-0803, Japan.
右背侧前额皮层 (DLPFC) 的跨直流刺激 (tDCS) 影响认知-运动双重任务的表现. 阴极tDCS损害了运动速度,而阳极tDCS在健康成年人中显示出改善的趋势.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 康复 康复 康复 康复
背景情况:
- 认知运动双重任务干扰 (DTi) 损害了日常功能,增加了跌倒的风险.
- 增加右背侧前额叶皮层 (DLPFC) 激活与DTi有关,但其作用尚不清楚.
研究的目的:
- 调查跨直流刺激 (tDCS) 对右侧DLPFC对认知运动双任务 (CMDT) 性能的影响.
- 为了确定正确的DLPFC刺激是否可以调节健康年轻成年人的CMDT表现.
主要方法:
- 这是一项双盲,随机化,模拟控制的试验,涉及74名健康的年轻人.
- 参与者进行了高负载CMDT (螺旋绘图 + 听觉工作记忆) 在阳极,阴极或虚拟tDCS下应用到右DLPFC.
- 行为结果包括运动速度和准确性,以及认知任务性能.
主要成果:
- 阴极tDCS显著降低了绘图速度,损害了电机性能.
- 阳极tDCS显示了改善电机性能的趋势.
- 没有观察到对绘图准确度或认知表现的显著影响. 较低的基线运动性能预测了更大的刺激效应.
结论:
- 正确的DLPFC刺激可以调节CMDT性能,具有极性依赖的效果.
- 右侧的DLPFC是增强认知运动功能的潜在神经调节目标.
- 结果表明,对于执行资源有限的人群,如老年人,有潜在的应用.
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