转录因子SPI1驱动免疫抑制的CD45+红色素原始细胞,以改善类风湿性关节炎

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Updated: Feb 22, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
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An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

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Wei-Hang Zhu1, Man-Li Wang1, Xia Meng1

  • 1Department of Rheumatology and Immunology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

RMD open
|February 20, 2026
PubMed
概括

CD45+红色素原生细胞 (EPC) 在类风湿性关节炎 (RA) 中扩大,并通过通过SPI1/TGF-β信号调节巨细胞来抑制炎症. 这些细胞代表了RA治疗的新型治疗标.

关键词:
关节炎,类风湿性关节炎自身免疫性疾病 自身免疫性疾病细胞因子 细胞因子

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