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Updated: Feb 22, 2026

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
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与APOE-ε4相关的认知衰退的遗传修饰剂

Alex G Contreras1,2, Skylar Walters1, Jaclyn M Eissman1,2

  • 1Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.

Nature communications
|February 20, 2026
PubMed
概括

研究人员确定了影响APOE-ε4等位基因,这是阿尔茨海默氏症的主要风险因素的个体的认知衰退的新基因. 这些遗传发现为保护大脑健康的干预提供了潜在的目标,特别是在多样化的人口中.

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