在精神分裂症中,CSF和血液中的突触基因的差异性DNA甲基化

Kirsten Jahn1, Adrian Groh2, Ole Riemer2

  • 1Laboratory of Molecular Neurosciences (LMN), Dept. of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany. Jahn.Kirsten@mh-hannover.de.

PubMed
概括

精神分裂症 (SZ) 的表观遗传变化会影响突触基因. 多巴胺载体 (DAT) 的DNA甲基化在SZ患者中较低,而后突触密度蛋白95 (PSD95) 的甲基化在他们的脑脊液中较高.

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