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联合抵抗和有氧运动计划是否会对患有乳腺癌的女性产生干扰效应? 一个系统审查和网络元分析
Pedro Lopez1,2,3,4, Anderson Rech5,6,7, Maria Petropoulou8
1Grupo de Pesquisa Em Exercício Para Populações Clínicas (GPCLIN), Universidade de Caxias do Sul, Caxias do Sul, Rio Grande do Sul, Brazil. pedro.lopezdacruz@resphealth.uwa.edu.au.
Sports medicine (Auckland, N.Z.)
|February 20, 2026
概括
对于乳腺癌患者来说,单独的抵抗运动 (RE) 可能比联合运动 (COMB) 更好,以保持肌肉质量和肌肉力量. 这种方法有助于尽量减少治疗期间潜在的干扰效应.
科学领域:
- 运动瘤学运动瘤学
- 癌症康复康复 癌症康复
- 乳腺癌治疗方法 乳腺癌治疗方法
背景情况:
- 运动医学对乳腺癌患者至关重要,抵抗运动 (RE) 提高肌肉力量,有氧运动 (AE) 提高心肺呼吸能力.
- 假设抵抗和有氧运动 (COMB) 的结合会引起干扰效应,可能会损害癌症患者的肌肉质量和肌肉力量的增加.
研究的目的:
- 研究COMB与RE对乳腺癌女性疲劳,肌肉质量,身体功能和肌肉力量的干扰效应.
- 检查影响这些结果的人口统计学,临床和运动处方调节者.
主要方法:
- 在7个数据库中进行了系统的搜索,截至2024年1月,在2025年4月进行了更新的搜索 (PROSPERO CRD42023491118).
- 使用随机效应网络元分析分析了涉及乳腺癌妇女的合格随机对照试验.
- 主要结局包括与癌症相关的疲劳,瘦身量,身体功能和下肢肌肉强度,干扰效应以差异>0.20标准化平均差异 (SMD) 表示.
主要成果:
- 与对照组相比,RE和COMB都类似地减少了疲劳. 在手术和化疗期间,RE对疲劳的益处比COMB更大.
- RE和COMB都改善了身体功能,RE在接受激素治疗的患者中表现出优越性.
- 虽然在主要分析中没有显著性,但灵敏度分析表明RE比COMB更倾向于肌肉质量和肌肉力量,特别是在排除异常值后.
结论:
- 根据治疗特征量身定制的个性化运动药物对患有乳腺癌的女性至关重要.
- 单独处方RE可能比COMB更好,以最大限度地减少对肌肉量和肌肉力量的潜在干扰影响,特别是在辅助和激素治疗期间.
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