儿童肺血栓栓塞的管理:一个基于证据的专家共识
Li-Nan Zeng1,2,3,4, Ying-Xue Zou5, Hai-Lin Zhang6
1Department of Pharmacy/Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University; Children's Medicine Key Laboratory of Sichuan Province, Chengdu, China.
World journal of pediatrics : WJP
|February 20, 2026
概括
缺乏针对儿科肺血栓塞栓症 (PTE) 的指导方针. 这份专家共识为儿童PTE的诊断和管理提供了建议,解决了关键护理需求.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 心血管医学 心血管医学
- 血液学 血液学 血液学
背景情况:
- 肺血栓塞栓症 (PTE) 是儿童罕见但危及生命的疾病.
- 目前没有针对儿科PTE的标准化诊断和管理指南.
- 这份专家共识解决了为儿科PTE提供基于证据的建议的需要.
研究的目的:
- 为儿童肺血栓栓塞的诊断和管理制定专家建议.
- 提供基于最好的可用证据的标准化方法.
主要方法:
- 使用了世界卫生组织指南制定手册.
- 一个由30名专家组成的专家小组进行了系统审查,并使用GRADE方法进行证据评估.
- 通过使用GRADE决策证据框架制定了建议.
主要成果:
- 对有关儿科PTE的20个临床问题提出了33个建议.
- 建议涵盖诊断,抗凝剂治疗,血栓溶解,干预程序和多学科护理.
- 建立了18个弱小的建议 (低质量的证据) 和15个良好实践声明.
结论:
- 提供了关于儿科PTE管理的专家建议,承认一般质量低且证据有限.
- 对于早期识别,诊断,预防,治疗和长期管理策略,迫切需要进一步的研究.
- 这种共识旨在改善患有肺血栓塞栓症的儿童的治疗结果.
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