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Updated: Feb 22, 2026

Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts
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库马林增强的醇混合物作为双抗癌和抗菌剂

Islam K Matar1,2, Magdi E A Zaki3, Zeinab A Muhammad4

  • 1Department of Chemistry, Saint Mary's University, Halifax, Nova Scotia, Canada.

Chemical biology & drug design
|February 21, 2026
PubMed
概括

新型 thiazol-hydrazono-coumarins 显示强大的抗菌活性对抗耐药细菌和选择性抗癌作用. 这些化合物向拓聚酶酶,为癌症患者治疗感染提供了希望.

关键词:
DNA 旋转酶 B 抑制剂它具有抗菌活性,具有抗菌活性.抗癌药物是一种抗癌药物.库马林衍生物库马林衍生物托波马酶II抑制剂的使用

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