患有前皮神经陷综合征的儿童的神经病理
Ashley Stoeckel1, Sanda Alexandrescu2, David P Mooney1
1Department of Surgery, Boston Children's Hospital, Boston, MA, USA.
概括
患有前皮神经陷综合征 (ACNES) 的儿童的神经病理显示出慢性神经损伤. 在ACNES治疗中,建议对受影响的神经进行切除,而不是简单释放.
科学领域:
- 儿科手术 儿科手术
- 神经病理学神经病理学
背景情况:
- 前皮神经陷综合征 (ACNES) 是儿童腹部疼痛的常见,但经常被忽视的原因.
- 参与ACNES的神经的病态状态尚不清楚,影响治疗决策.
研究的目的:
- 为了调查从被诊断患有ACNES的儿童切除的神经的组织病理学发现.
- 确定ACNES中神经是否有病理性变化,指导手术管理.
主要方法:
- 对从2011年12月到2023年9月前部神经切除病例的手术和病理学报告的回顾性审查.
- 评估了来自78名儿科患者的103个神经样本,其中包括29例重新手术的病例.
主要成果:
- 在103个评估的神经样本中,有71%的病理变化被发现.
- 常见的发现包括myxomatous变化 (69%),骨髓真空变性 (31%),周围神经纤维化 (21%).
- 一小部分标本 (4%) 缺乏可识别的神经组织.
结论:
- 在儿科ACNES病例中,大多数切割的神经都表现出改变,表明长期神经损伤远离被困部位.
- 与神经释放和保留相比,研究结果支持神经切除作为ACNES更合适的手术干预措施.
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