在内镜室内防止C. difficile的保护性屏障封闭:一个前性的,医院的干预研究
Quan Wen1, Sheng Zhang1, Yanfeng Zhao2
1Department of Microbiota Medicine & Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China.; Key Lab of Holistic Integrative Enterology, Jiangsu Engineering Research Center for Advanced Microbiota Medicine, Nanjing Medical University, Nanjing, 210011, Jiangsu, China.
概括
一项新的研究表明,使用一次性使用的全床防护屏障 (PBC) 显著减少了内镜室表面的Clostridioides difficile污染. 这种干预也降低了Clostridioides difficile感染 (CDI) 的发生率.
科学领域:
- 感染控制 感染控制
- 医疗保健相关的感染
- 临床微生物学 临床微生物学
背景情况:
- 在内镜室的高触摸表面可能被Clostridioides difficile污染.
- 需要有效的策略来防止Clostridioides difficile感染 (CDI) 在这些环境中传播.
研究的目的:
- 在中国内镜室的高触摸表面上调查Clostridioides difficile污染.
- 评估使用保护性屏障制 (PBC) 的有针对性干预对CDI率的影响.
主要方法:
- 这是一项针对中国三所高等医院的前性研究.
- 实时PCR用于检测转移床,治疗车,内镜主机和计算机外围设备上的Clostridioides difficile.
- 在一个中心实施了一次性全床PBC干预.
主要成果:
- 总体污染率为6.5%,转移床为17.2%.
- 在PBC实施后,转移床污染率降至0% (p=0.043).
- CDI发病率从每1000个患者日 (p=0.009) 的0.15下降到0.10个病例,预计可大大节省成本.
结论:
- 单次使用的全床PBC有效地减少了Clostridioides difficile污染和CDI发生率.
- 这种干预为内镜设置提供了一种实用且具有成本效益的感染控制解决方案.
相关概念视频
01:17Transmission-based Precautions I: Contact, Enteric, and Droplets
4.8K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
4.8K
01:22Healthcare Associated Infections II: Preventive Measures
4.4K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
4.4K
01:25Transmission-based Precautions II: Airborne and Protective Environment
2.0K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
2.0K
01:26Standard Precaution
3.2K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
3.2K
01:30Cleaning, Sterilization, and Disinfection
10.9K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
10.9K
01:18Surface Membrane Barriers
3.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
3.1K