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Updated: Feb 23, 2026

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
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Published on: August 23, 2019

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通过降低5'tiRNAGly-GCC生产的调节,DNMT2可以抑制类甲状腺癌的发生

Ruixin Zhou1,2, Baizhao Li1,2, Mingyu Cao1,2

  • 1Department of General Surgery, Xiangya Hospital of Central South University, Changsha, Hunan, China.

Cell death & disease
|February 21, 2026
PubMed
概括

减少的DNA甲基转移酶2 (DNMT2) 表达促进通过增加5'tiRNAGly-GCC. 这种分子准了 hnRNPH1,推动了瘤的进展. 抑制5'tiRNAGly-GCC显示了ATC的治疗潜力.

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