巴西结核病相关住院情况:在高负担环境中经历了9年的经验
Gabriela Pizarro Ossa Ferro Henriques1, Guilherme Barbosa Pinto1, Erika Yukie Ishigaki1
1Centro Universitário Faculdade de Medicina do ABC (FMABC), Disciplina de Infectologia, Santo André, SP, Brazil.
概括
巴西的结核病住院经常涉及社会脆弱和艾滋病毒共感染的个人,经常需要广泛的诊断工作. 早期检测和综合护理对于减少严重病例和改善患者结果至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 结核病 (TB) 仍然是一个重大的全球和巴西公共卫生挑战.
- 虽然门诊治疗是标准的,但由于严重的疾病,社会因素或并发症而导致住院.
研究的目的:
- 分析结核病相关住院治疗的特征和结果.
- 确定与严重结核病呈现和住院死亡率相关的因素.
主要方法:
- 2013-2022年在巴西圣保罗的197例结核病住院病人的回顾性观察性研究.
- 对流行病学,临床,实验室和微生物学数据的医疗记录的审查.
主要成果:
- 大多数住院患者 (73.1%) 是男性 (平均年龄为41.8岁). 结核病与艾滋病毒的同时感染很普遍 (55.3%),通常具有较低的CD4+计数.
- 观察到高水平的营养不良 (40.1%) 和物质使用 (吸烟64.0%,酒精51.6%,非法药物58.1%).
- 诊断工作是入院的主要原因 (74.1%),症状持续时间中位数为3.6个月. 住院死亡率为17.3%.
结论:
- 在这种情况下,结核病住院的情况与社会脆弱性,艾滋病毒共感染和诊断延迟有关.
- 严重的表现强调了早期检测和可访问的分子测试的必要性.
- 加强门诊和医院护理的整合可以减少住院治疗和改善结核病管理.
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