便携式电压测量方法用于在性介质中同时测定Δ9-Tetrahydrocannabinol和cannabidiol,使用未经修改的丝印碳电极
Mariane O Brandão1, Luciano C Arantes2, Camila D Lima1
1Departamento de Química, Universidade Federal Dos Vales Do Jequitinhonha e Mucuri, 39100-000, Diamantina, MG, Brazil.
Talanta
|February 22, 2026
概括
一种新的电化学方法使得使用碳丝网印刷的电极可以同时检测到delta-9-tetrahydrocannabinol (THC) 和cannabidiol (CBD). 这种快速,低成本的技术非常适合用于大麻产品的法医查和质量控制.
科学领域:
- 电分析化学 电分析化学
- 法医科学 法医科学 法医科学
- 大麻素分析分析
背景情况:
- 同时检测delta-9-tetrahydrocannabinol (THC) 和cannabidiol (CBD) 对于分析被扣押的大麻材料和产品至关重要.
- 现有的分析方法可能缺乏预先查所需的简单性,速度或成本效益.
研究的目的:
- 开发一种简单,快速和选择性的电化学方法,用于同时检测和量化THC和CBD.
- 为了验证该方法在现实世界法医和质量控制场景中的适用性.
主要方法:
- 在0.5mol L−1 NaOH性介质中使用未经修改的碳丝印刷电极 (碳-SPEs).
- 在广泛的pH范围内研究THC和CBD的电化学行为.
- 优化方形波电压测量 (SWV) 用于使用不同的氧化峰值 (THC的O1T,CBD的O3C) 进行同时测定.
主要成果:
- 达到了THC (O1T) 的0.09μmol L-1和CBD (O3C) 的2.72μmol L-1的检测极限.
- 已证明具有高可重现性,相对标准偏差 (RSD) 在峰值电流下低于5.6%,峰值电位下低于2.0%.
- 在35个被查获的样本和7种大麻产品上验证了该方法,与GC-MS分析和近100%的恢复率有很好的一致性.
结论:
- 开发的电化学方法提供了一种可靠,低成本和现场部署的工具,用于同时分析THC和CBD.
- 该技术适用于大麻衍生材料和产品的初步法医查和质量控制.
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