移植后心声学指数的变化:系统性审查和元分析
Achilleas Betsikos1, Marieta P Theodorakopoulou1, Maria Korogiannou2
1First Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
The American journal of the medical sciences
|February 22, 2026
概括
移植 (KTx) 与移植前水平相比,显著降低左心室质量指数 (LVMI). 这一发现表明,在末期病患者中,KTx可能会降低心血管风险.
科学领域:
- 腎臟病學 (nephrology) 是一種神經病學.
- 心脏病学 心脏病学
- 移植医学 移植医学
背景情况:
- 心血管疾病是末期病 (ESKD) 患者死亡的主要原因.
- 慢性病 (CKD) 与心肌病相关,显著增加心血管风险.
- 对ESKD患者来说,移植 (KTx) 提供了比透析更好的生存率.
研究的目的:
- 系统地审查和元分析KTx前后患者的心声回声指数变化.
- 评估KTx对左心室质量指数 (LVMI) 的影响.
主要方法:
- 在PubMed,Web-of-Science和Scopus数据库中进行全面的文献搜索.
- 包括手动参考搜索和灰色文献.
- 主要结果衡量主要集中在左心室质量指数 (LVMI).
主要成果:
- 涉及2364名患者的33项研究显示,KTx后的LVMI显著下降 (WMD -21.99 g/m2,P<0.00001).
- 在KTx后6个月内观察到较大的LVMI减少 (WMD-41.54g/m2) 与>6个月 (WMD-18.96g/m2) 相比.
- 在接受活体捐赠脏和在KTx之前接受血液透析的人群中,观察到较高的LVMI减少.
结论:
- 与移植前水平相比,KTx与LVMI的显著降低有关.
- 这种LVMI的减少可能有助于在KTx接受者与透析患者之间观察到的较低心血管风险.
相关概念视频
Kidney Transplant I: Introduction
552
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
552
Acute Kidney Injury IV: Diagnostic Studies and Prevention
364
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
364
Kidney Transplant III: Nursing Management
433
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
433
Acute Kidney Injury I: Introduction
877
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
877
Acute Kidney Injury II: Pathophysiology
1.3K
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
1.3K
Imaging Studies for Cardiovascular System I:Echocardiography
797
Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
797


