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Updated: May 5, 2026

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一种与HPV相关的新型直肠神经内分泌与非神经内分泌混合瘤

Ari Kassardjian1, Nafis Shafizadeh1, Wenjing Shi1

  • 1Department of Pathology, Southern California Permanente Medical Group, Woodland Hills Medical Center, Woodland Hills, California, USA.

International journal of surgical pathology
|February 22, 2026
PubMed
概括

这项研究报告了人类乳头瘤病毒 (HPV) 相关的直肠混合神经内分泌与非神经内分泌瘤 (MiNEN) 的第一个病例. 这些发现表明,HPV可能是这种罕见的胃肠道瘤的腺癌和神经内分泌成分的共同致癌驱动因素.

关键词:
人类乳头瘤病毒 人类乳头瘤病毒混合的神经内分泌非神经内分泌瘤.这是直肠腺癌 (Rectal Adenocarcinoma).这是直肠神经内分泌癌的癌.

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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