乳房切除术中的表面 (前面) 平面:一个低估的边缘变量,对局部复发有影响
1Head Breast Unit, Breast Unit, Surgery Department, West Lisbon Local Health Unit, Lisbon, Portugal. zsidiropoulou@ulslo.min-saude.pt.
Annals of surgical oncology
|February 22, 2026
概括
乳房切除样本的表面边缘通常含有残留的乳腺组织,增加了局部复发风险. 这种组织的标准化病理学文档可以澄清其作为真正的切除边缘的作用.
科学领域:
- 在瘤学瘤学.
- 手术病理学手术病理学
- 乳腺癌研究研究 乳腺癌研究
背景情况:
- 乳房切除标本的表面方面通常被视为解剖学界限.
- 病理学研究表明,在表面解剖平面上经常发现残留的乳腺组织或良性上皮质.
- 乳房切除术后大多数局部复发都发生在表面上,接近或涉及的边缘与复发风险增加有关.
研究的目的:
- 调查表面切除平面的组成 (皮肤/脂肪与纤维腺组织) 是否影响乳房切除术后局部复发风险.
- 提出表面平面组织的标准化病理学文档,以促进未来的研究.
主要方法:
- 审查现有的病理学采样研究和复发性映射数据.
- 关于在乳腺切除样本中表面平面组织组成的标准化文件的建议.
主要成果:
- 在皮肤节省乳腺切除术后,在53%的额外表面边缘标本中发现了良性乳腺上皮.
- 在76.2%的密集采样乳腺切除标本中检测到剩余的乳腺组织.
- 81.8%的乳房切除术后局部复发发生在表面皮肤/皮下组织中.
结论:
- 乳房切除标本的表面平面可能代表临床上显著的切除边缘,而不仅仅是一个解剖边界.
- 需要对表面平面组织组成的标准化病理学文件,以确定其对局部复发的影响.
- 这种文档可以允许对乳腺癌复发模式进行关键的回顾性和前性研究.
更多相关视频
13:35Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
4.5K
03:07Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
Published on: August 19, 2025
1.2K
相关概念视频
Comparing Experimental Results: Student's t-Test
The t-test is a statistical method used to compare the sample mean with a population mean or compare two means from two data sets. The test statistic is calculated from the standard deviation, mean, and number of measurements in the data set at a selected confidence interval and then compared to a table of critical values at this confidence level. If the test statistic is smaller than the critical value, the null hypothesis is accepted. In this case, we state that the difference between the...
Fineness of Cement
The fineness of cement directly influences the rate of hydration, as the hydration begins at the surface of the cement particles. In addition to hydration, the fineness of cement is vital for various properties of concrete including workability, gypsum requirement, and long-term behavior. The fineness of cement is represented in terms of the specific surface of cement which is typically measured in square meters per kilogram, with several methods available for this determination.
Direct...
Direct...
Fineness Modulus
The fineness modulus (FM) of aggregate is a numerical index that measures the coarseness or fineness of the particles. It is calculated by adding the cumulative percentages of aggregate retained on each of a specified series of sieves and dividing the sum by 100.
Consider performing sieve analysis on sand through a set of ASTM sieves. The weight of aggregate retained in each sieve and pan placed at the bottom is recorded, as given in Column B of Table 1.
To determine the fineness modulus of...
Consider performing sieve analysis on sand through a set of ASTM sieves. The weight of aggregate retained in each sieve and pan placed at the bottom is recorded, as given in Column B of Table 1.
To determine the fineness modulus of...
The Mean Value Theorem
The Mean Value Theorem establishes a fundamental connection between the overall change in a quantity and its change at a specific instant. It formalizes the idea that average change over an interval must be reflected by instantaneous change at some point within that interval. When a function behaves smoothly across a range, the theorem guarantees that this connection always exists.This relationship is captured mathematically by the Mean Value Theorem, as stated below.The meaning of this result...
First Derivative Test: Problem Solving
Imagine an asset price that crashes to a low point, rebounds sharply as bargain-hunters step in, and then gradually declines. Such behavior can be modeled with a smooth function whose turning points represent locally overvalued and undervalued regions. A convenient example that captures rebound followed by decay is:The high and low points of this curve are identified using the first derivative test, which determines where the function changes from increasing to decreasing or vice versa. To...
Interpretations of Partial Derivatives
A surface defined by a function of two variables can be visualized as a vast, uneven terrain, where each point is identified using Cartesian coordinates. The elevation of the terrain at any point is determined by a function that assigns a height value to every pair of horizontal coordinates. This representation allows the surface to be studied in terms of how its height varies across different directions.At a specific point on this terrain, understanding how the height changes requires...
