坚持不同的饮食模式和随后的总体,缺血和出血性中风风险
Sara Castro-Barquero1,2,3, Eric B Rimm1,4,5, Tudor G Jovin6
1Department of Nutrition (S.C.-B., E.B.R., M.A.M.-G.), Harvard T.H. Chan School of Public Health, Boston, MA.
Stroke
|February 23, 2026
概括
坚持地中海和地中海-DASH饮食显著降低高风险个体中风风险. 这项研究强调了这些健康饮食模式对总和缺血性中风的保护作用.
科学领域:
- 心血管流行病学心血管流行病学
- 营养科学 营养科学
- 预防医学 预防医学
背景情况:
- 饮食模式影响心血管疾病 (CVD) 的风险.
- 关于健康饮食和中风亚型的前性数据有限.
- 这项研究调查了饮食模式和中风发病率之间的关联.
研究的目的:
- 为了前性地研究坚持4种健康饮食模式与总和缺血性中风风险之间的关联.
- 在PREDIMED试验中分析高风险人群的数据.
主要方法:
- 对PREDIMED随机对照试验队列的二次分析 (n=7447).
- 对遵守地中海,DASH,地中海-DASH和行星健康饮食指数得分的评估.
- 使用多变量调整的考克斯比例危险模型来确定中风风险.
主要成果:
- 在31,024人年中,发生了135次中风 (112次缺血,23次出血).
- 遵守地中海和地中海-DASH饮食的最高水平显示,总中风风险显著降低 (HR分别为0.26和0.25).
- 对缺血性中风也观察到类似的减少;对于DASH或行星健康饮食指数没有显著的关联.
结论:
- 更多地坚持地中海和地中海-DASH饮食与减少总和缺血性中风风险有关.
- 这些发现支持了特定的健康饮食模式在高心血管疾病风险人群中中风预防中的作用.
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