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Emanuele Arcà¹, Adele Barlassina², Adaeze Eze¹

¹Strategic Market Access, OPEN Health, 3068 AV Rotterdam, The Netherlands.

Journal of market access & health policy

|February 23, 2026

概括

使用Delphi共识方法进行系统的PICOS范围调查,有效地将不同患者和国家观点集成到联合临床评估 (JCA) 中. 这种方法提高了医疗保健政策决策的透明度和可信度.

科学领域:

医疗技术评估 (HTA) 是指对医疗技术进行评估.
证据综合证据综合
患者参与政策中的参与.

背景情况:

根据欧盟医疗卫生技术法规,联合临床评估 (JCA) 需要对健康技术进行评估的强有力的框架.
整合不同利益相关者的观点,特别是患者,对于JCA的相关性和信誉至关重要.
PICOS (人口,干预,比较,结果,研究设计) 框架是确定JCA的关键工具.

研究的目的:

探索将结构化患者输入纳入JCA的PICOS范围确定过程中的可行性和价值.
通过使用Delphi共识方法,在JCA中运行系统的PICOS范围.
调和多个国家和患者的观点,使其成为HTA的共同框架.

主要方法:

一个经过修改的Delphi小组,包括来自12个欧盟成员国的12名患者专家.
在儿童脊髓肌肉缩的CAR-T疗法中建立关于PICOS元素的共识.
量化排名和定性反的代回合,以达成共识.

主要成果:

德尔菲过程成功地巩固了PICOS元素,并在各种患者专家之间达成共识.
患者参与强调了包容性资格,共享决策和护理人员观点的优先事项.
定性见解改进了对异见的理解,提高了透明度和科学有效性.

结论:

系统的PICOS范围与患者的输入是可行的和有价值的早期阶段欧盟HTA.
结构化的利益相关者参与提高了JCA的包容性,稳定性和相关性.
这种方法支持以患者为中心的证据生成和HTA的决策.

关键词:

卡特-T疗法是一种治疗方法.德尔菲的共识德尔菲的共识欧盟HTAR 欧盟HTAR 在线皮科斯 (PICOS) 的研究范围证据综合证据综合卫生技术评估卫生技术评估患者参与患者参与脊柱肌肉缩脊柱肌肉缩脊柱肌肉缩让利益相关者参与其中.

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