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Updated: Feb 24, 2026

Vibrational Spectra of a N719-Chromophore/Titania Interface from Empirical-Potential Molecular-Dynamics Simulation, Solvated by a Room Temperature Ionic Liquid
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Vibrational Spectra of a N719-Chromophore/Titania Interface from Empirical-Potential Molecular-Dynamics Simulation, Solvated by a Room Temperature Ionic Liquid

Published on: January 25, 2020

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解读蛋白离子液体和药物之间的相互作用:光谱,电化学和DFT探索线粒

Arti Sharma1, Ravinder Sharma1,2, Ritu1

  • 1Department of Chemistry, National Institute of Technology Hamirpur-177005 India sharmaravinder444@gmail.com.

RSC advances
|February 23, 2026
PubMed
概括

蛋白质离子液体 (ILs) 增强了心脏毒性较低的癌症药物米托克桑 (MTX) 的可溶性,稳定性和输送. 这项研究探讨了ILs作为改善药物配方的潜在制药辅助剂.

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Pore Transport and Ion-Pair Transport01:17

Pore Transport and Ion-Pair Transport

Pore transport and ion-pair formation are critical mechanisms for the absorption and distribution of drugs in the body.
Pore transport, also known as convective transport, is a process where small molecules like urea, water, and sugars rapidly cross cell membranes as though there were channels or pores in the membrane. Although direct microscopic evidence is limited  but the concept of pores or channels is widely accepted based on physiological evidence. Despite the lack of direct...
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Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry

Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
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