相关实验视频

Updated: Jul 28, 2026

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation
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Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Published on: September 20, 2017

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在PBMC-人性化NSG小鼠中进行两步算法选择跨物种序列不匹配的基于家庭养殖基因,以进行精确的基因表达评估

Minseong Jo1,2, Seo Yule Jeong1, Mi-Lang Kyun1

  • 1Center for Global Biopharmaceutical Research, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.

ACS omega
|February 23, 2026
PubMed
概括

选择稳定的家政基因对于在人性化小鼠模型中准确的基因表达分析至关重要. 这项研究确定了小鼠人类细胞的组织特异基因,提高了研究可靠性.

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Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

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Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens09:33

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens

Published on: August 25, 2023

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相关概念视频

Gene Conversion02:08

Gene Conversion

Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...