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欺凌受害者和大脑发育:从青春期到早期成年期的纵向结构磁共振成像研究
bioRxiv : the preprint server for biology
|February 23, 2026
概括
欺凌的受害者与大脑发育的改变有关,在一些区域 (如杏仁体) 加快增长,在其他区域 (如小脑) 减缓增长. 这些大脑变化显示了从青春期到成年早期的性别特异性模式.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 脑部成像 脑部成像
背景情况:
- 欺凌是青春期普遍存在的问题,可能会产生长期后果.
- 大脑发育持续到青春期和早期成年期,这是社会和情感成熟的关键时期.
- 了解像欺凌这样的不良经历对神经生物学影响对于公共卫生至关重要.
研究的目的:
- 调查欺凌受害和结构性大脑发育之间的纵向关联.
- 为了确定受欺凌受害者在青春期和成年早期受影响的特定大脑区域.
- 探索欺凌与大脑发育之间的关系中的潜在性别差异.
主要方法:
- 利用来自IMAGEN队列 (n = 2,094) 的纵向结构磁共振成像 (MRI) 数据.
- 在三个时间点 (青春期到早期成年期:~14,~19,和~22岁) 分析了大脑体积增长.
- 采用数据驱动分析,将欺凌受害者程度与大脑结构的变化联系起来.
主要成果:
- 更高的欺凌受害率与皮下皮层和边缘区域 (如皮,杏仁体,海马体,前带皮层) 的体积增长加速相关.
- 欺凌受害者也与小脑,内皮层和岛屿等区域体积增长的减少有关.
- 探索性分析揭示了性别特异性的模式:女性在情绪处理领域表现出更多的变化,而男性在运动/感官领域表现出更大的变化.
结论:
- 欺凌受害者与青春期和成年早期大脑发育的广泛,显著的结构差异有关.
- 这些发现突显了欺凌对神经生物学的影响,强调了它塑造大脑轨迹的潜力.
- 观察到的性别特异性差异表明,男性和女性的欺凌经历影响了不同的发育路径.
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