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Updated: Feb 24, 2026

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癌基因放大在86,000个癌细胞基因组中的演变

Jake June-Koo Lee, Sohrab Salehi, Matthew A Myers

    bioRxiv : the preprint server for biology
    |February 23, 2026
    PubMed
    概括

    癌症中的高水平拷贝数放大 (HLAMP) 源于不同的进化路径:染色体内放大 (ICamp) 和染色体外DNA (ecDNA). 了解这些途径是开发有效癌症疗法的关键.

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