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Updated: Feb 24, 2026

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
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Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage

Published on: August 21, 2021

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活细胞采用乌比奎丁-保护体系统和核酸切割修复途径去除反应性氧物种诱导的DNA-蛋白交叉链接 (ROS-DPCs)

Cesar I Cyuzuzo, Monica Kruk, Qi Zhang

    bioRxiv : the preprint server for biology
    |February 23, 2026
    PubMed
    概括

    活性氧物种 (ROS) 诱导的DNA-蛋白质交叉链接 (DPC) 是有毒的,而且人们对其了解甚少. 这项研究确定了参与ROS-DPC形成的蛋白质,并揭示了细胞修复机制,提供了潜在的治疗策略.

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