饮食纤维摄入量与癌症缓解症之间的关联:由炎症生物标志物调解
Yan Guo1,2,3, Caiyan Zhang1,2,3, Haiyue Wang2,3
1School of Public Health, Hebei Medical University, Shijiazhuang, China.
Frontiers in nutrition
|February 23, 2026
概括
较高的食纤维摄入量与减少癌症缓冲症风险有关. 炎症标志物部分介导这种保护作用,表明饮食纤维.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 炎症研究 炎症研究
背景情况:
- 癌症缓解症是癌症患者死亡的一个重要原因,由慢性炎症驱动.
- 食纤维具有抗炎性质,但其在癌症缓冲症风险中的作用尚不清楚.
研究的目的:
- 为了研究饮食纤维摄入量与癌症缓冲症风险之间的关联.
- 探索炎症标志物在食纤维和癌症缓解症之间关系中的调解作用.
主要方法:
- 从720名癌症患者中收集了饮食和临床数据.
- 限制立方线和多变量逻辑回归被用来分析关联.
- 进行中介分析以评估炎症的作用.
主要成果:
- 在饮食纤维摄入量和癌症缓解症风险之间发现了非线性反相关性 (p < 0.001).
- 增加的食纤维摄入量与较低的卡赫克西亚风险相关 (OR = 0.92,95% CI:0.87-0.98).
- 炎症标志物 (WBC,NEU,NLR) 介导了食纤维对缓冲症的影响 (5.67%-7.78%,p < 0.05).
结论:
- 增加食纤维摄入量可能会防止癌症缓解症,部分通过炎症途径.
- 建议对特定纤维类型和机制进行进一步的研究.
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