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Updated: Feb 24, 2026

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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RuPHOTACs为生物应用提供了对蛋白质降解的光控制,其性能优化了生物应用

Edith Glazer, Dmytro Havrylyuk, Ainsley LaMore

    Research square
    |February 23, 2026
    PubMed
    概括

    基于的PHOTOActivated Chimeras (RuPHOTACs) 提供光控制的蛋白质降解. 这种新的系统能够精确地控制PROTAC活动的时空,提高化学生物学应用的有效性和安全性.

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