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Updated: Feb 24, 2026

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
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多omics综合分析确定KIF22和KRAS是三阴性乳腺癌的高度合成致命对

Shichen Miao1,2, Xiao Wang3,4, Qiming Gu2

  • 1Department of Breast Surgery, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.

Frontiers in oncology
|February 23, 2026
PubMed
概括

研究人员在三阴性乳腺癌 (TNBC) 中发现了一种新的合成致命 (SL) 基因对,即KIF22和KRAS. 这一发现为TNBC提供了一个有前途的治疗标,有可能改善这种侵袭性癌症患者的治疗结果.

关键词:
机器学习是机器学习.多种主题的多种主题.合成杀伤性 合成杀伤性三重阴性乳腺癌是什么瘤异质性的异质性

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