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Updated: Feb 24, 2026

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IL1A增强了TNF诱导的视网膜质细胞死亡

Katherine M Andersh1,2,3, Michael MacLean4, Gareth R Howell4

  • 1Department of Ophthalmology, Flaum Eye Institute, University of Rochester Medical Center, Rochester, NY, United States.

Frontiers in aging neuroscience
|February 23, 2026
PubMed
概括

干白素-1α (IL1A) 能使眼睛对瘤亡因子 (TNF) 诱导的视网膜质细胞 (RGC) 死亡产生敏感性. 这种TNF诱导的RGC死亡的IL1A增强是SARM1依赖的,突出了对玻璃眼的新治疗标.

关键词:
玻璃眼 glaucoma 玻璃眼 玻璃眼 玻璃眼 玻璃眼介质蛋白 1 1 介质蛋白神经炎症是一种神经炎症.视神经病变是一种视神经病变.有关炎症的细胞因子.

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