2001-2021年期间的医疗补助受益人中,因艾滋病毒状况而导致的癌症手术后利用率,并发症和死亡率的差异
medRxiv : the preprint server for health sciences
|February 23, 2026
概括
接受癌症手术的艾滋病毒感染者 (PWH) 经历了医疗保健利用率的增加和更长的住院时间,但与没有艾滋病毒感染者 (PWoH) 相比,短期并发症类似. 然而,PWH在手术后面临更高的长期死亡风险.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 艾滋病毒感染者 (PWH) 可能面临比没有艾滋病毒感染者 (PWoH) 更糟糕的手术结果和更高的癌症死亡率.
- 之前的证据早于广泛采用全方位抗逆转录病毒疗法 (ART) 时代.
- 这项研究调查了PWH与接受癌症手术的PWoH的术后结果.
研究的目的:
- 为了比较癌症手术后的PWH和PWoH之间的术后结果.
- 评估治疗所有人ART时代对这些结果的影响.
- 为PWH癌症护理指南提供信息.
主要方法:
- 使用来自26个州的医疗补助数据 (2001-2021) 进行回顾性队列研究.
- 包括持续招募的成年人,接受各种癌症的首次住院/门诊手术.
- 分析结果:停留时间,再入院,ED使用,SSI和死亡率 (30天至5年).
主要成果:
- PWH (2.1% of 198,535) 的利用率更高:更长的LOS,更长的住院时间,更多的急救诊所.
- 在PWH和PWoH之间再录取,SSI或30天死亡率没有显著差异.
- PWH显示出更高的90天,1年和5年死亡率,特别是结肠直肠癌,尽管90天死亡率在ART时代减弱.
结论:
- 在癌症手术后,PWH使用率增加,但短期并发症类似.
- 支持目前用于PWH标准癌症护理的指南.
- 需要进一步的研究,以了解导致PWH手术后长期死亡率较高的因素.
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