开发和验证一种机器学习模型,用于预测老年关节骨折患者的手术前深静脉血栓形成
Xiaokang Wei1, Zehao Yin1, Shuqi Zhang1
1Department of Orthopedics, The First Hospital of Jilin University, Changchun, China.
Frontiers in medicine
|February 23, 2026
概括
使用XGBoost的机器学习模型在手术前在老年骨折患者中有效预测深静脉血栓 (DVT). 这种工具有助于进行手术前风险评估,并改善患者护理途径.
科学领域:
- 老年医学 老年医学
- 心血管外科心血管外科
- 医疗保健中的机器学习
背景情况:
- 老年人部骨折是一个重大的全球健康问题.
- 深静脉血栓 (DVT) 是一种常见的并发症,增加了手术风险和延迟治疗.
- 有效的手术前风险评估对于在这个人群中管理DVT至关重要.
研究的目的:
- 开发和验证一种机器学习模型,用于预测老年关节骨折患者的手术前DVT.
- 加强手术前评估,并简化这些患者的临床护理途径.
主要方法:
- 对782名老年关节骨折患者进行了回顾性研究.
- 使用五种监督机器学习算法 (DT,XGBoost,SVM,LightGBM,LR) 开发预测模型.
- 模型性能使用歧视,校准和临床适用性指标进行评估,用于可解释性使用SHAP.
主要成果:
- 在782名患者中,有186名患者 (23.8%) 患有DVT.
- XGBoost模型实现了卓越的预测准确性 (AUC 0.829培训,0.808验证).
- 关键预测因素包括受伤到入院的时间,D-二聚体,血红蛋白,白蛋白和APTT水平.
结论:
- XGBoost模型在老年关节骨折患者的手术前DVT预测方面表现出很高的性能.
- SHAP分析提高了模型的解释性,而基于网络的工具提高了临床适用性.
- 这种预测工具可以帮助临床医生进行风险分层和医疗决策.
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