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Updated: May 6, 2026

Quantitative Phosphoproteomics in Fatty Acid Stimulated Saccharomyces cerevisiae
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Pho-Tip:为快速和灵敏地分析 DIA 蛋白质组学数据的单一脱化

Katharina D Faisst1, Kate Lau1, Ludwig R Sinn1,2

  • 1Quantitative Proteomics Laboratory, Department of Biochemistry, Charité - Universitätsmedizin Berlin, Berlin 10117, Germany.

Analytical chemistry
|February 23, 2026
PubMed
概括

Pho-Tip是一种新的去化方法,简化了 DIA 蛋白组学数据的分析. 这种技术改善了低丰度酸化的检测,使定量分析更加有效.

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相关概念视频

Phosphorylation01:02

Phosphorylation

The addition or removal of phosphate groups from proteins is the most common chemical modification that regulates cellular processes. These modifications can affect the structure, activity, stability, and localization of proteins within cells as well as their interactions with other proteins.
During phosphorylation, protein kinases transfer the terminal phosphate group of ATP to specific amino acid side chains of substrate proteins. Serine, threonine, and tyrosine are the most commonly...
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