Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

364
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
364
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

877
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
877
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

1.3K
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
1.3K
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

1.0K
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
1.0K
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

534
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
534
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

378
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
378

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

How to Transform a Health System's Organizational Culture and Hardwire It for the Future.

NEJM catalyst innovations in care delivery·2026
Same author

Figure-of-eights vs running suture for fascial closure of large ventral hernias: do figure-of-eights induce ischemia?

Surgical endoscopy·2026
Same author

Impact of Fostamatinib on Inflammatory Biomarkers in Hospitalized Patients With COVID-19.

Critical care explorations·2026
Same author

Mitigating bias in the analysis and inferences from using longitudinal EHR data in disease outcomes research.

BMC medical research methodology·2026
Same author

Restarting Medications After Deprescribing in Adults Discharged From Hospital to Skilled Nursing.

JAMA network open·2026
Same author

Swab Testing to Optimize Pneumonia Treatment With Empiric Vancomycin: A Randomized Controlled Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026

相关实验视频

Updated: Feb 24, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.9K

在广泛的手术群体中,术后急性损伤的风险预测模型.

Matthew S Shotwell1, Cassandra Hennessy1, Barbara J Martin2

  • 1Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN.

Journal of the American College of Surgeons
|February 23, 2026
PubMed
概括
此摘要是机器生成的。

这项研究使用手术患者数据开发了术后急性损伤 (AKI) 的预测模型. 该模型准确地识别高风险患者,使得有针对性的干预措施能够减少AKI的发生率和成本.

关键词:
急性脏损伤急性脏损伤是什么在术后的术后生活.风险预测风险预测

更多相关视频

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
07:03

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury

Published on: February 15, 2022

1.8K
Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
03:13

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research

Published on: November 3, 2023

3.1K

相关实验视频

Last Updated: Feb 24, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.9K
Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
07:03

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury

Published on: February 15, 2022

1.8K
Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
03:13

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research

Published on: November 3, 2023

3.1K

科学领域:

  • 腎臟病學 (nephrology) 是一種醫學專業.
  • 手术结果研究研究.
  • 医疗信息学 医疗信息学

背景情况:

  • 手术后急性损伤 (AKI) 是一种严重的并发症,影响患者的康复,增加发病率,死亡率和医疗保健费用.
  • 预测模型提供了一种有希望的方法来缓解手术患者的AKI风险.

研究的目的:

  • 开发和验证一个监督学习模型,用于预测在接受手术的患者中AKI的风险.
  • 利用美国外科医生学院国家外科质量改进计划 (ACS-NSQIP) 数据库进行模型开发和验证.

主要方法:

  • 来自田纳西外科质量协作 (TSQC) (2020-2023) 的12家医院的数据被用于培训和时间验证.
  • 从2023年ACS-NSQIP参与者使用数据文件 (PUF) 中获得了一个外部验证集.
  • 选择了一个附加物流模型,排除了先前透析或ASA分类为5的患者;AKI是由术后功能障碍或30天内透析定义的.

主要成果:

  • 该研究分析了59,706个培训案例和980,323个外部验证案例,其AKI率分别为1.8%和2.4%.
  • 添加物流模型在两个验证集中实现了0.87-0.88的曲线下的面积 (AUC).
  • 关键预测AKI包括住院状态,,功能衰竭,手术前肌,败血症,美国麻醉学会 (ASA) 分类和患者年龄.

结论:

  • 开发的模型显示了强大的预测性能 (歧视和校准) 术后的AKI.
  • 这种工具可以在手术前识别高风险患者,促进针对性的术后干预.
  • 需要进一步的研究来验证和在不同的临床环境中实施该模型,以减少AKI发生率和相关成本.