大血管血管炎主要影响下肢:一系列病例和文献综述
Johanne H Egedal1,2, André H Dias3, Pieter H Nienhuis4
1Department of Internal Medicine, Regional Hospital Horsens, Horsens.
概括
大血管血管炎 (LVV) 可以影响下肢 (LE),呈现异常. 早期考虑LE血管炎对于诊断和管理至关重要,即使没有经典症状.
科学领域:
- 类风湿病学 类风湿病学
- 血管医学 血管医学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 先进的成像揭示了非典型的大血管血管炎 (LVV) 模式,具有挑战性的诊断和管理.
- 主要影响下肢 (LE) 的LVV是一种不常见的表现.
- 这项研究侧重于LE占主导地位的LVV的病因,诊断和治疗.
研究的目的:
- 描述和分析主要涉及下肢的LVV病例.
- 审查关于LE占主导地位的LVV的现有文献.
- 讨论这种罕见表现的诊断和治疗含义.
主要方法:
- 通过使用18F-氧葡萄糖-正电子发射断层扫描/计算机断层扫描 (FDG-PET/CT) 追溯识别LE参与的LVV患者.
- 使用PubMed搜索相关案例报告的文献搜索.
- 临床表现和管理策略的比较.
主要成果:
- 分析了16名患者 (8例新病例,8例文献报告).
- 大多数患者有非特异性症状;只有60%的人报告了LE的症状,例如音.
- 对症状患者开始治疗,在一些无症状或较小血管血管炎病例中观察到自发改善.
结论:
- 在患有LE炎症,疼痛或硬度的患者中,应考虑影响下肢的血管炎.
- 自发改善可能会发生,特别是在没有巨细胞关节炎 (GCA) 典型症状的患者中.
- 早期识别是对LE占主导地位的LVV进行适当管理的关键.
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