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用CRISPR关联的转子子用于可编程的病毒载体工程和原始编辑

Quyen T Dang1, Chin-Wei Chang1, Pin-Yan Chen1

  • 1Department of Chemical Engineering, National Tsing Hua University, Hsinchu 300044, Taiwan.

Nucleic acids research
|February 23, 2026
PubMed
概括

SHOT 2.0 是一种新的CRISPR相关的转子子平台,用于E. coli中的灵活的细菌工程. 这种工具可以在各种细胞类型中实现高效的基因传递和原始编辑,从而扩大了baculovirus的应用.

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