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Updated: Feb 24, 2026

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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调节重建揭示了阿尔茨海默氏症疾病中的新型放松调节因素

Marcella Vitória Belém-Souza1,2, Gustavo Barra-Matos1,2, Gilderlanio Santana de Araújo3,4

  • 1Graduate Program in Genetics and Molecular Biology, Institute of Biological Sciences, Federal University of Pará, Belém, 66075-100, Brazil.

Molecular neurobiology
|February 23, 2026
PubMed
概括

这项研究绘制了阿尔茨海默氏症 (AD) 中的转录因子网络图,确定了关键主调节器 (MR-TFs),该调节器在大脑区域中协调基因放松调节. 这些发现为了解AD的复杂分子机制提供了基础.

关键词:
阿尔茨海默氏症的疾病是阿尔茨海默氏症.监管转录网络 监管转录网络转录因子 转录因子

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