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Updated: Feb 25, 2026

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs
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在神经发育障碍中阐明疾病机制的方法.

Ashley B Durbin1, Philip H Iffland2

  • 1Department of Neurology, University of Maryland School of Medicine.

Journal of visualized experiments : JoVE
|February 23, 2026
PubMed
概括

新的基因编辑和干细胞技术为理解和治疗神经发育障碍 (NDD) 提供了希望. 这些先进的方法对于发现新的疾病机制和全球数百万受影响的治疗点至关重要.

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Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
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