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Updated: May 7, 2026

Pentylenetetrazole-Induced Kindling Mouse Model
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由Akr1a缺乏症引起的索胺积累 驱动侵略性和多动性

Kyoka Iino1, Kazuya Toriumi2, Mitsuhiro Miyashita3

  • 1Schizophrenia Research Project, Department of Clinical Medical Sciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan; Department of Igakuken Disease-oriented Molecular Biology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.

Neuroscience letters
|February 23, 2026
PubMed
概括

像托 (PEN) 一样,高级糖化终产物 (AGEs) 在代谢压力下积累. 在Akr1a淘汰赛小鼠中,大脑中PEN升高与侵略性和过度活跃性相关,模拟了与精神分裂症相关的行为.

关键词:
这就是AKR1A1A1的原因.攻击性 侵略性 攻击性葡萄糖酸是什么 葡萄糖酸是什么过度活跃性 这是一种过度活跃性的现象.索西丁是一种索西丁.精神分裂症是一种精神分裂症.

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