预防口腔癌的干预措施:一个证据和差距地图
Suzanne Tanya Nethan1, Maria Eduarda Pérez-de-Oliveira2, Fiona Campbell3
1IARC Handbooks Programme, Evidence Synthesis and Classification Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
International journal of cancer
|February 23, 2026
概括
口腔癌预防策略需要改进. 在无烟烟草 (SLT) 和烟草戒烟,控制政策和二次预防方面存在研究缺口,特别是在年轻人中.
科学领域:
- 公共卫生 公共卫生
- 预防癌症 预防癌症
- 流行病学 流行病学
背景情况:
- 口腔癌是一个重要的全球健康问题,是全球第16个最常见的癌症.
- 目前的口腔癌预防工作面临局限性,需要对现有研究进行全面审查,并确定知识差距.
研究的目的:
- 系统地绘制证据并确定五个关键口腔癌干预类别的研究差距.
- 为公共卫生决策提供信息,并指导制定针对性,基于证据的口腔癌预防策略.
主要方法:
- 开发五个证据和差距地图,利用国际癌症研究机构的188项研究.
- 基于干预措施的研究分类:预防性饮食剂,风险因素戒烟,无烟烟草 (SLT) 和果戒烟,SLT/果控制政策和二次预防.
主要成果:
- 最受研究的领域是戒烟风险因素 (57项研究) 和控制政策 (51项研究).
- 发现了重大研究缺陷,包括对年轻人的有限研究,SLT/阿雷卡戒断后的风险逆转,阿雷卡戒断干预,阿雷卡戒断政策和高风险个人的查.
结论:
- 在多个SLT领域和区域坚果控制领域,特别是高负担地区,急需进一步的研究.
- 解决发现的研究缺口可以导致更有效,基于证据的公共卫生战略,以减少全球口腔癌的负担.
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