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Updated: Feb 25, 2026

Laser Microdissection Applied to Gene Expression Profiling of Subset of Cells from the Drosophila Wing Disc
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Published on: April 30, 2010

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单细胞和空间转录学定义了丝虫翅膀盘中的20E驱动的发育重编程

Qingsong Liu1, Mingmin He2, Hao Chen1

  • 1Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Chongqing Technology Innovation Center of Breeding, Biological Science Research Center, Southwest University, Chongqing, China.

Nature communications
|February 23, 2026
PubMed
概括

科学家使用单细胞分析绘制了丝虫翅膀发育的地图. 他们确定了关键的细胞类型和转变,揭示了激素如何控制潜在农业应用的器官生成.

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Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012...
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