结核病颗粒瘤中细胞组织和细菌控制的免疫代谢拓

Erin F McCaffrey1,2, Alea C Delmastro3, Isobel Fitzhugh4

  • 1Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA. erin.mccaffrey@nih.gov.

Nature immunology
|February 23, 2026
PubMed
概括

结核菌颗粒瘤创造了一个独特的低氧环境,阻碍了免疫反应,促进了Mycobacterium结核菌的持久性. 这种缺氧与细菌负载增加和颗粒瘤内的免疫功能障碍相关.

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